This is the Linux app named qure whose latest release can be downloaded as QuRe_v0.99971.zip. It can be run online in the free hosting provider OnWorks for workstations.
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SCREENSHOTS:
qure
DESCRIPTION:
QuRe is a program for viral quasispecies reconstruction, specifically developed to analyze long read (>100 bp) NGS data. The software performs alignments of sequence fragments against a reference genome, finds an optimal division of the genome into sliding windows based on coverage and diversity and attempts to reconstruct all the individual sequences of the viral quasispecies--along with their prevalence--using a heuristic algorithm, which matches multinomial distributions of distinct viral variants overlapping across the genome division. QuRe comes with a built-in Poisson error correction method and a post-reconstruction probabilistic clustering, both parameterized on given error rates in homopolymeric and non-homopolymeric regions.This is an application that can also be fetched from https://sourceforge.net/projects/qure/. It has been hosted in OnWorks in order to be run online in an easiest way from one of our free Operative Systems.