This is the Linux app named SPINA whose latest release can be downloaded as SPINAThyr4.2.1Source.zip. It can be run online in the free hosting provider OnWorks for workstations.
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SCREENSHOTS:
SPINA
DESCRIPTION:
SPINA is software for the rapid, reliable and accurate determination of constant structure parameters of endocrine feedback control systems. It is a class of static function tests that require nothing more than steady-state concentrations of hormones or metabolites obtained in vivo.
The first version of this cybernetic approach had been developed for the evaluation of the functional status of the thyroid gland, i.e. thyroid's secretory capacity (gain of thyroid, GT or SPINA-GT) and sum activity of peripheral deiodinases (GD or SPINA-GD).
A second version has been established for insulin-glucose homeostasis. It delivers the secretory capacity of pancreatic beta cells (SPINA-GBeta), an estimate for the insulin receptor amplification (SPINA-GR) and a static disposition index as a measure for the loop gain of the feedback loop (SPINA-DI).
Both implementations of SPINA have been validated in more than 50 clinical studies based on large cohorts.
Features
- More than 25 years of continued development
- Based on published parametrically isomorphic models of thyroid and insulin-glucose homeostasis
- Algorithms evaluated in more than 50 clinical trials with thousands of patients
- Suport for different units of measurement
- Data import and export in HL7 format
- Curated by SciScrunch, OpenAIRE and Zenodo
- Cross-platform for macOS, Windows and Linux
- DOI 10.5281/zenodo.3596049 https://doi.org/10.5281/zenodo.3596049 (SPINA Thyr)
- DOI 10.5281/zenodo.15249620 https://doi.org/10.5281/zenodo.15249620 (SPINA Carb)
Audience
Healthcare Industry, Science/Research, Education, End Users/Desktop, Other Audience
User interface
Gnome, Win32 (MS Windows), Cocoa (MacOS X), Handheld/Mobile/PDA, Carbon (Mac OS X)
Programming Language
Pascal, Delphi/Kylix, Object Pascal, S/R, Lazarus, Free Pascal
Database Environment
XML-based, Flat-file
Categories
This is an application that can also be fetched from https://sourceforge.net/projects/spina/. It has been hosted in OnWorks in order to be run online in an easiest way from one of our free Operative Systems.