This is the Linux app named reditools whose latest release can be downloaded as REDItools-1.2.1.zip. It can be run online in the free hosting provider OnWorks for workstations.
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REDItools are python scripts developed with the aim to study RNA editing at genomic scale by next generation sequencing data. RNA editing is a post-transcriptional phenomenon involving the insertion/deletion or substitution of specific bases in precise RNA localizations. In human, RNA editing occurs by deamination of cytosine to uridine (C-to-U) or mostly by the adenosine to inosine (A-to-I) conversion through ADAR enzymes. A-to-I substitutions may have profound functional consequences and have been linked to a variety of human diseases including neurological and neurodegenerative disorders or cancer. NGS technologies offer a unique opportunity to investigate RNA editing. REDItools are simple python scripts conceived to investigate RNA editing at large-scale.
REDItools are now hosted at https://github.com/BioinfoUNIBA/REDItools
- RNA editing
This is an application that can also be fetched from https://sourceforge.net/projects/reditools/. It has been hosted in OnWorks in order to be run online in an easiest way from one of our free Operative Systems.