This is the Windows app named OpenGrowth to run in Windows online over Linux online whose latest release can be downloaded as OpenGrowth_Manual_1.0.pdf. It can be run online in the free hosting provider OnWorks for workstations.
Download and run online this app named OpenGrowth to run in Windows online over Linux online with OnWorks for free.
Follow these instructions in order to run this app:
- 1. Downloaded this application in your PC.
- 3. Upload this application in such filemanager.
- 4. Start any OS OnWorks online emulator from this website, but better Windows online emulator.
- 6. Download the application and install it.
OpenGrowth to run in Windows online over Linux online
DESCRIPTIONOpenGrowth is a research program which grows new ligands in proteins by connecting small organic fragments. The details can be found in the original publication "OpenGrowth: an automated and rational algorithm for finding new protein ligands" (J. Med. Chem., http://dx.doi.org/10.1021/acs.jmedchem.5b00886).
To use OpenGrowth, you will need OpenGrowth_1.0.zip and Resources_1.0.2.zip that can be found by clicking on the Files menu in the horizontal bar at the top (https://sourceforge.net/projects/opengrowth/files). OpenGrowthGUI, FOG2.0, and the 3Mer-Screen stand-alone can be found in OpenGrowth_1.0.zip. To prepare new fragments you need BuildingFragments_1.0.1.zip and the scripts for MD simulations are in MD-Scripts_1.0.1.zip. SMoG2016.tar.gz allows to compute a score with the newly developed function (J. Chem. Inf. Mod., http://pubs.acs.org/doi/abs/10.1021/acs.jcim.6b00610).
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- Drug design
Healthcare Industry, Science/Research, End Users/Desktop
This is an application that can also be fetched from https://sourceforge.net/projects/opengrowth/. It has been hosted in OnWorks in order to be run online in an easiest way from one of our free Operative Systems.