This is the Linux app named LFSpro whose latest release can be downloaded as LFSpro_1.0.3.zip. It can be run online in the free hosting provider OnWorks for workstations.
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DESCRIPTIONIdentifying TP53 mutation carrier is critical to people with Li-Fraumeni syndrome for cancer prevention and survival improvement. A new method is needed for clinical counselors because of the limitations of current clinical criteria. LFSpro is built on a Mendelian model and estimates the TP53 mutation probability through Elston-Stewart algorithm with accuracy. Unlike previously used models, our model incorporates de novo mutation rate, which greatly improved estimation accuracy.
This is an application that can also be fetched from https://sourceforge.net/projects/lfspro/. It has been hosted in OnWorks in order to be run online in an easiest way from one of our free Operative Systems.