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MCPerm: Monte Carlo SNP permutation to run in Windows onl

Free download MCPerm: Monte Carlo SNP permutation  to run in Windows online over Linux online Windows app to run online win Wine in Ubuntu online, Fedora online or Debian online

This is the Windows app named MCPerm: Monte Carlo SNP permutation to run in Windows online over Linux online whose latest release can be downloaded as MCPerm_1.1.2.tar.gz. It can be run online in the free hosting provider OnWorks for workstations.

Download and run online this app named MCPerm: Monte Carlo SNP permutation to run in Windows online over Linux online with OnWorks for free.

Follow these instructions in order to run this app:

- 1. Downloaded this application in your PC.

- 2. Enter in our file manager https://www.onworks.net/myfiles.php?username=XXXXX with the username that you want.

- 3. Upload this application in such filemanager.

- 4. Start any OS OnWorks online emulator from this website, but better Windows online emulator.

- 5. From the OnWorks Windows OS you have just started, goto our file manager https://www.onworks.net/myfiles.php?username=XXXXX with the username that you want.

- 6. Download the application and install it.

- 7. Download Wine from your Linux distributions software repositories. Once installed, you can then double-click the app to run them with Wine. You can also try PlayOnLinux, a fancy interface over Wine that will help you install popular Windows programs and games.

Wine is a way to run Windows software on Linux, but with no Windows required. Wine is an open-source Windows compatibility layer that can run Windows programs directly on any Linux desktop. Essentially, Wine is trying to re-implement enough of Windows from scratch so that it can run all those Windows applications without actually needing Windows.

MCPerm: Monte Carlo SNP permutation to run in Windows online over Linux online


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DESCRIPTION

MCPerm: A Monte Carlo permutation method for multiple test correlation in case-control association study
Traditional permutation (TradPerm) test is an important non-parametric analysis method which can be treated as the gold standard for multiple testing corrections in case-control association study. However, it relies on the original single nucleotide polymorphism (SNP) genotypes and phenotypes data to perform a large number of random shuffles, and thus it is computationally intensive, especially for genome-wide association study (GWAS). To improve the calculation speed without changing the size of the TradPerm p-value, we developed a Monte Carlo permutation (MCPerm) method as an efficient alternative to TradPerm.
Methods: MCPerm does not need to shuffle the original genotypes and phenotypes data. It uses Monte Carlo method, employs two-step hypergeometric distribution to generate the random number of genotypes (AA, Aa and aa) in cases and controls.

Programming Language

S/R



This is an application that can also be fetched from https://sourceforge.net/projects/mcperm/. It has been hosted in OnWorks in order to be run online in an easiest way from one of our free Operative Systems.


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