This is the Windows app named Virus whose latest release can be downloaded as Qspp_v1.zip. It can be run online in the free hosting provider OnWorks for workstations.
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Virus
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DESCRIPTION
Stochastic simulation model of poliovirus Sabin-to-Mahoney genetic state transition (C++ code). Models genotypes, virus populations, and quasispecies cloud. Simulates replication error and copy-choice recombination. Various parameters guiding the model are user-specified. Python code post-processes simulation output to produce report files.
Features
- Simulates Picornavirus replication error and copy-choice recombination
- Represents genotypes, cell populations, and quasispecies cloud
- Allows user control of parameters: MOI, replication error rate, recombination rate, generational growth rate, burst size, number of passages, number of cells, fitness acceleration, Mahoney mutational synergy
- Reports population diversity, average fitness, neurovirulence, Mahoney resemblence
Audience
Science/Research, Education, Advanced End Users, Developers
Programming Language
Python, C++
Categories
This is an application that can also be fetched from https://sourceforge.net/projects/qspp-modeling/. It has been hosted in OnWorks in order to be run online in an easiest way from one of our free Operative Systems.
